Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633995 | 0.87 | MAPT (0.38) | GRM4AVPR2HSD17B10CHRM5CHRM1 | |
| SCHEMBL8634664 | 0.86 | GRM4 (0.46) | GRM4HSD17B10SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8632058 | 0.78 | ALDH1A1 (0.43) | GRM4AVPR2LMNAHSD17B10CHRM5 | |
| SCHEMBL8633396 | 0.78 | CHRM5 (0.41) | GRM4AVPR2LMNAHSD17B10CHRM5 | |
| SCHEMBL8628426 | 0.78 | LMNA (0.44) | GRM4AVPR2LMNAHSD17B10CHRM5 | |
| SCHEMBL8631926 | 0.78 | AVPR2 (0.44) | GRM4AVPR2LMNAHSD17B10CHRM5 | |
| Hydrochloric Acid SCHEMBL8661678 | 0.76 | AVPR2 (0.52) | AVPR2LMNACHRM5CHRM1CHRM3 | |
| SCHEMBL8632070 | 0.76 | GRM4 (0.40) | GRM4AVPR2LMNAHSD17B10CHRM5 | |
| Hydrochloric Acid SCHEMBL8631929 | 0.75 | AVPR2 (0.51) | AVPR2LMNACHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8634036 | 0.75 | AVPR2 (0.51) | AVPR2LMNACHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705333-A | Peptide-based nucleic acid mimics(PENAMS) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1996004000-A1 | PEPTIDE-BASED NUCLEIC ACID MIMICS (PENAMs) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-02-15 | — | — | WO | disclosed |