SCHEMBL8632081

SCHEMBL8632081

ClC(Cl)=CCOc1ccc(Oc2cccc(Br)c2)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.40
RAB9A P51151 4/20 0.38
NPC1 O15118 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
KMT2A Q03164 3/20 0.38
HPGD P15428 3/20 0.38
MEN1 O00255 2/20 0.38
GRM4 Q14833 1/20 0.38
TP53 P04637 1/20 0.38
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 2/20 0.37
PPARA Q07869 1/20 0.37
MAPT P10636 1/20 0.37
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36
KCNH2 Q12809 1/20 0.36
RECQL P46063 1/20 0.36
MAOB P27338 3/20 0.36
KMO O15229 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632023 0.90 PPARD (0.40) PPARDRAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL8634621 0.88 MAOB (0.37) RAB9ANPC1SMN1; SMN2HPGDGRM4
SCHEMBL8634454 0.87 PPARD (0.40) PPARDKMT2AMEN1PPARAMAPT
SCHEMBL8635697 0.85 ALDH1A1 (0.46) PPARDRAB9ANPC1KMT2AHPGD
SCHEMBL8632019 0.85 FFAR4 (0.47) PPARDPPARA
SCHEMBL8635410 0.84 HSP90AA1 (0.46) PPARAHTR2ASLC6A4KCNH2KMO
SCHEMBL8635684 0.82 TDP1 (0.42) PPARDSMN1; SMN2KMT2AHPGDMEN1
SCHEMBL8633930 0.81 TDP1 (0.38) PPARDL3MBTL1TSHRPPARAHTR2A
SCHEMBL8635559 0.80 PPARA (0.50) PPARDRAB9ANPC1PPARAHTR2A
SCHEMBL8636578 0.80 HTR2A (0.41) PPARDRAB9ANPC1HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed