SCHEMBL21628442

SCHEMBL21628442

Cc1ccc(Oc2ccc(C(=O)O)cc2F)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.61
LMNA P02545 1/20 0.61
HTT P42858 1/20 0.61
RAB9A P51151 1/20 0.61
IGFBP3 P17936 2/20 0.58
TTR P02766 2/20 0.51
MRGPRX4 Q96LA9 1/20 0.49
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PPARG P37231 1/20 0.46
RXRA P19793 1/20 0.46
PARP10 Q53GL7 1/20 0.45
MMP13 P45452 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA7 P43166 1/20 0.45
TPMT P51580 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21274603 0.87 LMNA (0.60) MAPK1LMNAHTTRAB9ATTR
SCHEMBL30816841 0.87 LMNA (0.60) MAPK1LMNAHTTRAB9ATTR
SCHEMBL21628730 0.86 PARP10 (0.59) MAPK1LMNAHTTRAB9AIGFBP3
SCHEMBL29242843 0.86 LMNA (0.58) MAPK1LMNAHTTRAB9AIGFBP3
SCHEMBL30951059 0.86 LMNA (0.58) MAPK1LMNAHTTRAB9AIGFBP3
SCHEMBL3130872 0.85 TTR (0.68) MAPK1LMNAHTTRAB9AIGFBP3
SCHEMBL21628782 0.85 TDP1 (0.54) MAPK1LMNAHTTRAB9AIGFBP3
SCHEMBL26563282 0.84 RXRA (0.55) RAB9ATTRMRGPRX4ALDH1A1SMN1; SMN2
SCHEMBL19357374 0.84 RAB9A (0.56) MAPK1LMNAHTTRAB9AIGFBP3
SCHEMBL21628711 0.84 LMNA (0.56) MAPK1LMNAHTTRAB9AIGFBP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-12-21 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2022-11-03 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPK1 3508/4885LMNA 3327/4885HTT 550/4885
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPK1 3508/4885LMNA 3327/4885HTT 550/4885
US-11591289-B2 Aromatic compounds AHR, TYR, MUSK MAPK1 3401/4885LMNA 3083/4885HTT 304/4885
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPK1 3508/4885LMNA 3327/4885HTT 550/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR MAPK1 2406/4885LMNA 832/4885HTT 703/4885
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPK1 3508/4885LMNA 3327/4885HTT 550/4885
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPK1 3508/4885LMNA 3327/4885HTT 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.