Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841627 | 0.86 | MAOB (0.41) | KDM4ESMN1; SMN2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL15430848 | 0.83 | HTR1A (0.57) | HTR1AKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL3291614 | 0.81 | ESR1 (0.54) | ESR1 | |
| SCHEMBL1930261 | 0.80 | KMT2A (0.55) | KDM4ESMN1; SMN2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL14747883 | 0.79 | ESR1 (0.49) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL9651856 | 0.79 | IDO1 (0.44) | HTR1AKDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL12587297 | 0.79 | BACE1 (0.43) | KMT2AHPGDMEN1MAPTESR1 | |
| SCHEMBL14925311 | 0.79 | MAOB (0.44) | KDM4EKMT2AMAPTHTTESR1 | |
| SCHEMBL9445435 | 0.79 | KDM4E (0.40) | HTR1AKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12412237 | 0.77 | ESR1 (0.56) | KDM4EALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143366-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2012-03-27 | — | — | US | disclosed |