SCHEMBL841627

SCHEMBL841627

COCCOCCOCCOCCOc1ccc(O)cc1OCCOCCOCCOCCOC

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.41
EGFR P00533 1/20 0.41
L3MBTL1 Q9Y468 6/20 0.41
MAPT P10636 4/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
KMT2A Q03164 1/20 0.41
CHRNB4 P30926 2/20 0.40
CHRNA3 P32297 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 3/20 0.40
FGFR1 P11362 1/20 0.39
FLT1 P17948 1/20 0.39
LMNA P02545 2/20 0.38
MAPK1 P28482 1/20 0.38
KDM4E B2RXH2 5/20 0.38
FDPS P14324 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL863233 0.86 HTR1A (0.45) EGFRL3MBTL1MAPTTDP1MEN1
SCHEMBL14925311 0.81 MAOB (0.44) MAOBEGFRMAPTKMT2AFGFR1
SCHEMBL5298028 0.81 ALDH1A1 (0.45) EGFRMAPTMEN1KMT2ASMN1; SMN2
SCHEMBL13933168 0.80 L3MBTL1 (0.59) L3MBTL1MAPTTDP1MEN1NPC1
SCHEMBL19708262 0.80 L3MBTL1 (0.59) L3MBTL1MAPTTDP1MEN1NPC1
SCHEMBL19025103 0.79 L3MBTL1 (0.37) MAOBL3MBTL1TDP1MEN1KMT2A
SCHEMBL15595766 0.79 ALDH1A1 (0.48) MAOBL3MBTL1MAPTTDP1MEN1
SCHEMBL15384783 0.79 SLC6A4 (0.49) MAOBEGFRL3MBTL1MAPTMEN1
SCHEMBL22964315 0.79 L3MBTL1 (0.50) MAOBEGFRL3MBTL1MAPTMEN1
SCHEMBL17525544 0.79 MAPT (0.50) L3MBTL1MAPTTDP1MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651163-B1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LTD (IN) 2015-03-04 EP disclosed
US-8143366-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2012-03-27 US disclosed
US-20100081782-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME EKWURIBE NNOCHIRI N 2010-04-01 US disclosed
US-7625995-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2009-12-01 US disclosed
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LIMITED (IN) 2008-06-19 US disclosed
EP-1651163-A4 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LTD (IN) 2008-03-26 EP disclosed
US-7335751-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2008-02-26 US disclosed
US-20060167234-A1 Aryl carbamate oligomers for hydroilyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2006-07-27 US disclosed
EP-1651163-A2 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME Nobex Corporation (US) 2006-05-03 EP disclosed
WO-2005016240-A2 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME NOBEX CORPORATION (US) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167234-A1 Aryl carbamate oligomers for hydroilyzable prodrugs and prodrugs comprising same ALK, OGFR, AOX1 MAOB 1113/4885EGFR 1194/4885L3MBTL1 647/4885
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME ALK, AOX1, OGFR MAOB 498/4885EGFR 1286/4885L3MBTL1 655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.