Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632340 | 1.00 | DGAT1 (0.35) | DGAT1LSSSMN1; SMN2RAB9AAR | |
| SCHEMBL8629066 | 0.84 | ADRA1D (0.34) | SMN1; SMN2RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL8629068 | 0.84 | ADRA1D (0.34) | SMN1; SMN2RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL8632344 | 0.83 | DGAT1 (0.38) | DGAT1SMN1; SMN2RAB9AATMMAPT | |
| SCHEMBL8630195 | 0.81 | SLC6A9 (0.38) | MAPTKDM4EGAAHPGD | |
| SCHEMBL8630198 | 0.81 | SLC6A9 (0.38) | MAPTKDM4EGAAHPGD | |
| SCHEMBL8631720 | 0.76 | ERN1 (0.33) | — | |
| SCHEMBL8631716 | 0.76 | ERN1 (0.33) | — | |
| SCHEMBL8650089 | 0.76 | HPGD (0.36) | SMN1; SMN2RAB9AMAPTKDM4EHPGD | |
| SCHEMBL8650094 | 0.76 | HPGD (0.36) | SMN1; SMN2RAB9AMAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705243-B1 | BETA-AMINOVINYL KETONES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BETA DIKETONES | RHONE POULENC AGROCHIMIE (FR) | 1998-06-24 | — | — | EP | disclosed |
| US-5684206-A | CONDENSING METHYL ORGANO KETONE WITH A BENZONITRILE IN PRESENCE OF STRONG BASE | RHONE-POULENC ARGOCHIMIE (FR) | 1997-11-04 | — | — | US | disclosed |
| EP-0705243-A1 | BETA-AMINOVINYL KETONES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BETA DIKETONES | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000476-A1 | BETA-AMINOVINYL KETONES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BETA DIKETONES | RHONE POULENC AGROCHIMIE (FR) | 1995-01-05 | — | — | WO | disclosed |