Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631498 | 0.95 | TSHR (0.43) | TSHRLMNAMAPK1USP2ATM | |
| SCHEMBL8627942 | 0.88 | TSHR (0.43) | TSHRLMNAMAPK1USP2ATM | |
| SCHEMBL8632930 | 0.87 | TSHR (0.45) | TSHRLMNAMAPK1USP2ATM | |
| SCHEMBL8867663 | 0.84 | TSHR (0.41) | TSHRLMNAMAPK1USP2ATM | |
| SCHEMBL8629030 | 0.83 | TSHR (0.41) | TSHRLMNAMAPK1USP2ATM | |
| Hydrochloric Acid SCHEMBL8632521 | 0.82 | LMNA (0.38) | TSHRLMNAMAPK1USP2ATM | |
| SCHEMBL8628591 | 0.81 | LOXL2 (0.41) | TSHRLMNAMAPK1USP2ATM | |
| SCHEMBL7468643 | 0.76 | TSHR (0.42) | TSHRALDH1A1MAOB | |
| SCHEMBL8633614 | 0.76 | TP53 (0.41) | TSHRLMNAMAPK1USP2ATM | |
| SCHEMBL8627411 | 0.75 | TSHR (0.44) | TSHRLMNAMAPK1USP2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | claimed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |