Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632952 | 0.93 | SIRT1 (0.41) | LOXL2TSHRMAPK1LMNAL3MBTL1 | |
| SCHEMBL8631498 | 0.86 | TSHR (0.43) | MAPTTSHRMAPK1LMNAUSP2 | |
| SCHEMBL8627942 | 0.79 | TSHR (0.43) | MAPTTSHRMAPK1LMNAL3MBTL1 | |
| SCHEMBL8629030 | 0.77 | TSHR (0.41) | MAPTTSHRMAPK1LMNAL3MBTL1 | |
| SCHEMBL8632930 | 0.74 | TSHR (0.45) | MAPTTSHRMAPK1LMNAL3MBTL1 | |
| SCHEMBL18581793 | 0.71 | THRB (0.59) | MAPTTSHRMAPK1LMNAL3MBTL1 | |
| SCHEMBL8628594 | 0.70 | TRPA1 (0.43) | LOXL2MAPTL3MBTL1NPSR1POLB | |
| SCHEMBL8635431 | 0.70 | TP53 (0.43) | MAPTTSHRMAPK1LMNAL3MBTL1 | |
| SCHEMBL7469321 | 0.69 | TSHR (0.58) | LOXL2MAPTTSHRMAPK1LMNA | |
| SCHEMBL8628121 | 0.68 | ALDH1A1 (0.38) | MAPTTSHRMAPK1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |