Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806801 | 0.92 | LMNA (0.70) | LMNACA2CA9NR1H2KDM4E | |
| SCHEMBL9806781 | 0.84 | LMNA (0.81) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL19950727 | 0.80 | NR1H2 (0.67) | NR1H2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11402428 | 0.78 | KDM4E (0.61) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL4234504 | 0.78 | LMNA (0.67) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL5151001 | 0.77 | KDM4E (0.71) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL31259847 | 0.77 | KDM4E (0.71) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL2300546 | 0.77 | S100A4 (0.57) | CA2CA9CA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9807394 | 0.74 | LMNA (0.65) | LMNACA2CA9NR1H2KDM4E | |
| SCHEMBL29226172 | 0.73 | NR1H2 (0.59) | LMNANR1H2KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853635-A1 | BRANCHED BLOCK ETHYLENE POLYMERS, THEIR PREPARATION AND COMPOSITIONS COMPRISING THE SAME | THE DOW CHEMICAL COMPANY (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997012919-A1 | BRANCHED BLOCK ETHYLENE POLYMERS, THEIR PREPARATION AND COMPOSITIONS COMPRISING THE SAME | THE DOW CHEMICAL COMPANY (US) | 1997-04-10 | — | — | WO | disclosed |