Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | CA9 | Q16790 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632760 | 0.92 | LMNA (0.64) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL9806781 | 0.89 | LMNA (0.81) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL4234504 | 0.79 | LMNA (0.67) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL31259847 | 0.79 | KDM4E (0.71) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL5151001 | 0.79 | KDM4E (0.71) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL9807394 | 0.78 | LMNA (0.65) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL9806804 | 0.77 | ALDH1A1 (0.48) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL2890255 | 0.77 | KMT2A (0.56) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11402428 | 0.77 | KDM4E (0.61) | LMNACA2CA9KDM4ECYP1A2 | |
| SCHEMBL5846779 | 0.76 | LMNA (0.61) | LMNACA2CA9KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061780-A | Poly(ether-bis-imide-spiro dilactam) polymer | SHELL OIL COMPANY (US) | 1991-10-29 | — | — | US | disclosed |