Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702148 | 0.96 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL11391053 | 0.94 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 | |
| Sulfuric Acid SCHEMBL8632857 | 0.83 | HRH4 (0.32) | ALDH1A1L3MBTL1TDP1MAPTLMNA | |
| Sulfuric Acid SCHEMBL6545764 | 0.83 | S100B (0.46) | ALDH1A1L3MBTL1TDP1MAPTLMNA | |
| Sulfuric Acid SCHEMBL10702698 | 0.82 | S100B (0.44) | ALDH1A1L3MBTL1TDP1MAPTLMNA | |
| Sulfuric Acid SCHEMBL5157371 | 0.82 | S100B (0.44) | ALDH1A1L3MBTL1TDP1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL10825979 | 0.82 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 | |
| SCHEMBL10518294 | 0.80 | TP53 (0.47) | ALDH1A1TSHRMAPK1CYP3A4MAPT | |
| Sulfuric Acid SCHEMBL8625325 | 0.80 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 | |
| SCHEMBL8081030 | 0.78 | S100B (0.53) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240371-B2 | Method of processing lightsensitive silver halide photographic material | KONISHIROKU PHOTO IND (JP) | 1996-01-31 | — | — | EP | disclosed |
| EP-0286850-B1 | METHOD FOR PREVENTING AN ORGANIC COLORED SUBSTANCE FROM FADING BY LIGHT, STABILIZED COLORED COMPOSITIONS AND PHOTOGRAPHIC ELEMENTS AND MATERIALS | KONICA CORPORATION (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5082765-A | Developers containing aromatic primary amines in combination w ith sensitizers | KONICA CORPORATION (JP) | 1992-01-21 | — | — | US | disclosed |