Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628591 | 0.93 | LOXL2 (0.41) | MAPK1ALDH1A1TSHRTHRBTP53 | |
| SCHEMBL8631498 | 0.84 | TSHR (0.43) | MAPK1ALDH1A1TSHRTHRBTP53 | |
| SCHEMBL8632487 | 0.80 | TSHR (0.41) | MAPK1ALDH1A1TSHRTHRBTP53 | |
| SCHEMBL8627942 | 0.78 | TSHR (0.43) | MAPK1ALDH1A1TSHRTP53LMNA | |
| SCHEMBL8629030 | 0.78 | TSHR (0.41) | MAPK1ALDH1A1TSHRTP53LMNA | |
| SCHEMBL8867663 | 0.73 | TSHR (0.41) | MAPK1ALDH1A1TSHRTHRBTP53 | |
| SCHEMBL8632930 | 0.73 | TSHR (0.45) | MAPK1ALDH1A1TSHRTP53LMNA | |
| SCHEMBL18581793 | 0.72 | THRB (0.59) | MAPK1ALDH1A1SMN1; SMN2TSHRTHRB | |
| SCHEMBL8635431 | 0.70 | TP53 (0.43) | MAPK1ALDH1A1TSHRTP53LMNA | |
| SCHEMBL18593269 | 0.69 | TSHR (0.60) | MAPK1ALDH1A1SMN1; SMN2TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |