Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637680 | 0.82 | — | — | |
| SCHEMBL8630922 | 0.82 | IDO1 (0.45) | — | |
| SCHEMBL8634340 | 0.74 | CES2 (0.43) | — | |
| SCHEMBL8630561 | 0.74 | PNMT (0.41) | — | |
| SCHEMBL20858622 | 0.72 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL8633064 | 0.70 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL8636206 | 0.70 | TACR1 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24168852 | 0.69 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL16571060 | 0.69 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL3118322 | 0.69 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |