Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632053 | 0.83 | — | — | |
| SCHEMBL8636206 | 0.80 | TACR1 (0.37) | — | |
| SCHEMBL8634340 | 0.74 | CES2 (0.43) | — | |
| SCHEMBL8632991 | 0.74 | SLC6A2 (0.46) | — | |
| SCHEMBL4157268 | 0.73 | PNMT (0.58) | PNMTEPHX1 | |
| SCHEMBL8630922 | 0.72 | IDO1 (0.45) | — | |
| SCHEMBL29750658 | 0.68 | HTR2C (0.54) | PNMT | |
| SCHEMBL27698385 | 0.68 | PNMT (0.48) | PNMTEPHX1 | |
| SCHEMBL8633793 | 0.65 | SLC6A2 (0.47) | — | |
| SCHEMBL27698323 | 0.65 | EPHX1 (0.46) | PNMTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |