Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631214 | 0.83 | — | — | |
| SCHEMBL8630561 | 0.74 | PNMT (0.41) | — | |
| SCHEMBL8632991 | 0.74 | SLC6A2 (0.46) | — | |
| SCHEMBL377011 | 0.73 | CES2 (0.62) | CES2LMNAHSD11B1MGLLGAA | |
| SCHEMBL8630922 | 0.72 | IDO1 (0.45) | — | |
| SCHEMBL8990303 | 0.71 | — | — | |
| SCHEMBL7418491 | 0.69 | HSD11B1 (0.56) | CES2LMNAHSD11B1MGLL | |
| Hydrochloric Acid SCHEMBL11517089 | 0.68 | HTR2C (0.56) | CES2LMNAHSD11B1MGLL | |
| SCHEMBL7456011 | 0.67 | CES2 (0.53) | CES2LMNAHSD11B1MGLL | |
| SCHEMBL12832452 | 0.66 | CES2 (0.56) | CES2LMNAHSD11B1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |