Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 6/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636228 | 0.90 | AGTR2 (0.40) | AGTR2AGTR1MMEAPLNR | |
| SCHEMBL8639183 | 0.84 | AGTR2 (0.42) | AGTR2AGTR1MME | |
| SCHEMBL8633065 | 0.83 | AGTR2 (0.49) | AGTR2AGTR1 | |
| SCHEMBL9010417 | 0.75 | AGTR2 (0.42) | AGTR2AGTR1MME | |
| SCHEMBL9010408 | 0.74 | AGTR2 (0.55) | AGTR2AGTR1 | |
| SCHEMBL8636224 | 0.73 | AGTR2 (0.46) | AGTR2AGTR1 | |
| SCHEMBL8636030 | 0.73 | AGTR1 (0.48) | AGTR2AGTR1MME | |
| SCHEMBL9427433 | 0.72 | AGTR2 (0.41) | AGTR2AGTR1MME | |
| SCHEMBL9010419 | 0.72 | APLNR (0.38) | APLNR | |
| SCHEMBL8976447 | 0.70 | AGTR2 (0.50) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776964-A | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |