Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430109 | 0.87 | SLC1A3 (0.36) | KMT2AMEN1TSHR | |
| SCHEMBL8633109 | 0.75 | TAAR1 (0.37) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8633106 | 0.72 | SLC1A3 (0.37) | KMT2AMEN1L3MBTL1ALDH1A1CYP2C9 | |
| SCHEMBL15693935 | 0.71 | KMT2A (0.53) | KMT2AMEN1MAPTALDH1A1TSHR | |
| SCHEMBL22262820 | 0.71 | MEN1 (0.61) | KMT2AMEN1ATMALDH1A1THRB | |
| SCHEMBL15693937 | 0.71 | KMT2A (0.53) | KMT2AMEN1MAPTALDH1A1TSHR | |
| SCHEMBL8573838 | 0.70 | MEN1 (0.34) | KMT2AMEN1 | |
| SCHEMBL13181798 | 0.69 | KMT2A (0.55) | KMT2AMEN1MAPTL3MBTL1ATM | |
| SCHEMBL12770520 | 0.69 | KMT2A (0.55) | KMT2AMEN1MAPTL3MBTL1ATM | |
| SCHEMBL8570991 | 0.67 | ALDH1A1 (0.41) | KMT2AMEN1MAPTL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712388-A | Method of preparing a derivative of optically active azetidin-2-one | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-01-27 | — | — | US | disclosed |