Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430109 | 0.82 | SLC1A3 (0.36) | TAAR1APAF1MEN1KMT2ATSHR | |
| SCHEMBL8633102 | 0.75 | KMT2A (0.48) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL8631335 | 0.71 | — | — | |
| SCHEMBL8633106 | 0.68 | SLC1A3 (0.37) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL16057295 | 0.65 | SLC1A3 (0.46) | KDM4ETDP1 | |
| SCHEMBL708488 | 0.65 | ALDH1A1 (0.35) | TAAR1ALDH1A1LMNATDP1TSHR | |
| SCHEMBL16057294 | 0.65 | SLC1A3 (0.46) | KDM4ETDP1 | |
| SCHEMBL17476051 | 0.65 | SLC1A3 (0.46) | KDM4ETDP1 | |
| SCHEMBL706260 | 0.64 | ESR1 (0.37) | ALDH1A1LMNATDP1TSHRL3MBTL1 | |
| SCHEMBL4275381 | 0.63 | MAPT (0.35) | TAAR1ALDH1A1KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712388-A | Method of preparing a derivative of optically active azetidin-2-one | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-01-27 | — | — | US | disclosed |