Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290470 | 0.91 | CYP11B1 (0.47) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL29897853 | 0.87 | CYP11B1 (0.51) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL6280771 | 0.87 | CYP11B1 (0.51) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL6280690 | 0.79 | CYP11B1 (0.47) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL29897870 | 0.79 | CYP11B1 (0.47) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL6285696 | 0.77 | CYP11B1 (0.49) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL30666830 | 0.74 | CYP11B1 (0.53) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL6287169 | 0.73 | CYP11B1 (0.54) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL30487694 | 0.73 | CYP11B1 (0.54) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL4269308 | 0.69 | PTGS2 (0.46) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802935-A4 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | UNIV LELAND STANFORD JUNIOR (US) | 1998-09-30 | — | — | EP | claimed |
| EP-0802935-A1 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1997-10-29 | — | — | EP | claimed |
| WO-1995025757-A1 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1995-09-28 | — | — | WO | claimed |