Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883484 | 0.97 | PTPRB (0.45) | NPSR1KDM4EMAPTIDO1TDP1 | |
| SCHEMBL8633540 | 0.96 | IDO1 (0.46) | NPSR1KDM4EMAPTIDO1TDP1 | |
| SCHEMBL8632625 | 0.87 | IDO1 (0.46) | NPSR1KDM4EMAPTIDO1TDP1 | |
| SCHEMBL8633442 | 0.82 | TDP1 (0.42) | NPSR1KDM4EMAPTTDP1CA12 | |
| SCHEMBL20590258 | 0.81 | TDP1 (0.58) | NPSR1KDM4EMAPTIDO1TDP1 | |
| SCHEMBL8630758 | 0.80 | IDO1 (0.44) | NPSR1IDO1TDP1PTPRBDRD2 | |
| SCHEMBL8636980 | 0.80 | LMNA (0.43) | NPSR1MAPTTDP1CYP3A4MAOA | |
| Ethyl Benzoate SCHEMBL28125723 | 0.80 | KDM4E (0.52) | NPSR1KDM4EMAPTIDO1TDP1 | |
| Ethyl Benzoate SCHEMBL28244856 | 0.80 | KDM4E (0.52) | NPSR1KDM4EMAPTIDO1TDP1 | |
| SCHEMBL8329540 | 0.79 | IDO1 (0.50) | NPSR1MAPTIDO1PTPRBSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | claimed |
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |