Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633540 | 0.89 | IDO1 (0.46) | IDO1PTPRBSYKCYP2D6TDP1 | |
| SCHEMBL8633439 | 0.87 | NPSR1 (0.46) | IDO1PTPRBSYKTDP1NPSR1 | |
| SCHEMBL8630758 | 0.84 | IDO1 (0.44) | IDO1PTPRBSYKCYP2D6TDP1 | |
| SCHEMBL8883484 | 0.84 | PTPRB (0.45) | IDO1PTPRBSYKTDP1NPSR1 | |
| SCHEMBL8633833 | 0.79 | SYK (0.40) | IDO1SYKCYP2D6TDP1NPSR1 | |
| SCHEMBL8457758 | 0.78 | IDO1 (0.62) | IDO1SYKCYP2D6TDP1HTR1A | |
| SCHEMBL8633442 | 0.77 | TDP1 (0.42) | SYKTDP1NPSR1MAPTKDM4E | |
| SCHEMBL7430220 | 0.75 | SYK (0.49) | IDO1SYKCYP2D6TDP1HTR1A | |
| SCHEMBL8329540 | 0.74 | IDO1 (0.50) | IDO1PTPRBSYKNPSR1MAPT | |
| SCHEMBL8636641 | 0.74 | KDM4E (0.53) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | claimed |