Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633442 | 0.96 | TDP1 (0.42) | SYKMEN1GAAKMT2ATDP1 | |
| SCHEMBL8633540 | 0.81 | IDO1 (0.46) | SYKMEN1GAAKMT2ATDP1 | |
| SCHEMBL8632625 | 0.79 | IDO1 (0.46) | SYKGAATDP1NPSR1MALT1 | |
| SCHEMBL8633439 | 0.77 | NPSR1 (0.46) | SYKTDP1NPSR1IDO1MAPT | |
| SCHEMBL8630069 | 0.76 | MEN1 (0.48) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL8883484 | 0.75 | PTPRB (0.45) | SYKTDP1NPSR1IDO1MAPT | |
| SCHEMBL8630758 | 0.75 | IDO1 (0.44) | SYKMEN1GAAKMT2ATDP1 | |
| SCHEMBL8633561 | 0.72 | TDP1 (0.48) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL14985078 | 0.70 | IDO1 (0.52) | MEN1GAAKMT2ATDP1NPSR1 | |
| SCHEMBL1467340 | 0.69 | NAAA (0.56) | MEN1GAAKMT2ATDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | claimed |