Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632567 | 0.80 | GFER (0.39) | MAPTNPSR1ITGB3ITGA2BCYP2C9 | |
| SCHEMBL7450096 | 0.80 | ITGB3 (0.42) | ITGB3ITGA2BCYP2C9SMN1; SMN2MAPK1 | |
| SCHEMBL8636934 | 0.79 | MAPT (0.36) | MAPTNPSR1ITGB3ITGA2BCYP2C9 | |
| Hydrochloric Acid SCHEMBL8637210 | 0.79 | GFER (0.38) | MAPTNPSR1ITGB3ITGA2BMAPK1 | |
| SCHEMBL7398021 | 0.75 | ITGB3 (0.39) | ITGB3ITGA2BCYP2C9SMN1; SMN2MAPK1 | |
| SCHEMBL7403452 | 0.73 | ITGB3 (0.37) | ITGB3ITGA2BCYP2C9SMN1; SMN2MAPK1 | |
| SCHEMBL8634865 | 0.72 | GAA (0.38) | MAPTNPSR1MEN1KMT2ATSHR | |
| SCHEMBL8698839 | 0.70 | FAAH (0.37) | NPSR1ITGB3ITGA2BCYP2C9SMN1; SMN2 | |
| SCHEMBL8637925 | 0.70 | GFER (0.38) | MAPK1ALDH1A1TSHRADAMTS5MMP2 | |
| SCHEMBL8630686 | 0.70 | ITGB3 (0.37) | ITGB3ITGA2BCYP2C9SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |