Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634964 | 0.87 | NAMPT (0.46) | KMT2ALMNASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8629786 | 0.79 | KDM4E (0.45) | KMT2ALMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL8634426 | 0.78 | FDPS (0.52) | KMT2ATDP1SMN1; SMN2MAPK1CHRNA7 | |
| SCHEMBL8631399 | 0.74 | LMNA (0.45) | KMT2ALMNATDP1SMN1; SMN2MAPK1 | |
| SCHEMBL30335358 | 0.73 | LMNA (0.52) | KMT2ALMNATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5861404 | 0.73 | ALDH1A1 (0.50) | KMT2ALMNATDP1SMN1; SMN2MAPK1 | |
| SCHEMBL8636980 | 0.72 | LMNA (0.43) | KMT2ALMNATDP1SMN1; SMN2MAPK1 | |
| SCHEMBL7057410 | 0.71 | ALDH1A1 (0.48) | KMT2ALMNATDP1SMN1; SMN2MAPK1 | |
| SCHEMBL5860273 | 0.71 | CYP1A2 (0.54) | KMT2ALMNATDP1SMN1; SMN2MAPK1 | |
| SCHEMBL27564027 | 0.71 | CYP1A2 (0.57) | KMT2ALMNATDP1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |