Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634552 | 0.88 | ALDH1A1 (0.46) | KDM4EMAPTCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL8634964 | 0.82 | NAMPT (0.46) | KDM4EMAPTALDH1A1SMN1; SMN2CHRM5 | |
| SCHEMBL8633560 | 0.79 | KMT2A (0.47) | MAPTALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL8633579 | 0.78 | CYP1A2 (0.51) | KDM4EMAPTCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL8631399 | 0.76 | LMNA (0.45) | MAPTCYP1A2ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL21025180 | 0.74 | CYP1A2 (0.53) | KDM4EMAPTCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8636980 | 0.74 | LMNA (0.43) | MAPTCYP1A2ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL5140898 | 0.71 | CYP1A2 (0.48) | KDM4ECYP1A2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5862781 | 0.71 | ALDH1A1 (0.47) | KDM4EMAPTCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11168807 | 0.71 | POLB (0.42) | KDM4EMAPTCYP1A2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |