Cyclohexylamine

Cyclohexylamine

SCHEMBL8633674

NC1CCCCC1.O=C(O)C(CC1CCCCC1)OC1CCCCO1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SELE P16581 4/20 0.38
SLC1A3 P43003 3/20 0.34
SLC1A2 P43004 3/20 0.34
SLC1A1 P43005 3/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PPARG P37231 2/20 0.32
PPARA Q07869 2/20 0.32
CTSL P07711 1/20 0.32
CTSB P07858 1/20 0.32
CTSH P09668 1/20 0.32
CPB2 Q96IY4 1/20 0.32
METAP2 P50579 1/20 0.31
METAP1 P53582 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6484046 0.93 SELE (0.39) SELESLC1A3SLC1A2SLC1A1MEN1
Cyclohexylamine SCHEMBL8637515 0.79 SRR (0.45) PPARGPPARA
SCHEMBL8638477 0.78 MEN1 (0.40) MEN1KMT2ACTSLCTSBCTSH
SCHEMBL29087904 0.77 MEN1 (0.38) MEN1KMT2A
SCHEMBL30638082 0.77 MEN1 (0.38) MEN1KMT2A
Cyclohexylamine SCHEMBL8636821 0.77 MEN1 (0.32) MEN1KMT2A
SCHEMBL1610399 0.76 MEN1 (0.37) MEN1KMT2APPARGPPARA
SCHEMBL9044977 0.73 MEN1 (0.36) MEN1KMT2APPARGPPARA
SCHEMBL1996227 0.71 TET2 (0.35) MEN1KMT2A
SCHEMBL4100097 0.71 CA2 (0.38) MEN1KMT2APPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5760235-A DIPEPTIDES BASED ON PROLINE OR PIPECOLIC ACID AND ARGININE ALDEHYDE GYOGYSZERKUTATO INTEZET KFT. (HU) 1998-06-02 US disclosed
EP-0629212-B1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF GYOGYSZERKUTATO INTEZET (HU) 1997-10-08 EP disclosed
EP-0629212-A1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF. GYOGYSZERKUTATO INTEZET (HU) 1994-12-21 EP disclosed
WO-1993018060-A1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF Gyógyszerkutató Intézet Kft. (HU) 1993-09-16 WO disclosed