Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.48 |
| ▸ | CA9 | Q16790 | 12/20 | 0.48 |
| ▸ | CA12 | O43570 | 11/20 | 0.48 |
| ▸ | CA1 | P00915 | 9/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.46 |
| ▸ | CA5A | P35218 | 3/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627552 | 0.76 | PTGS2 (0.50) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL8629241 | 0.74 | CA2 (0.40) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL8628373 | 0.71 | CA2 (0.51) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL12692373 | 0.67 | CA12 (0.86) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL202948 | 0.65 | CA2 (0.81) | CA2CA9CA12CA1CA5A | |
| SCHEMBL11623852 | 0.65 | PTGS2 (0.66) | PTGS2 | |
| SCHEMBL2605787 | 0.65 | CA1 (1.00) | CA2CA9CA12CA1PTGS2 | |
| P-Toluenesulfonamide SCHEMBL31527821 | 0.64 | CA2 (1.00) | CA2CA9CA12CA1PTGS2 | |
| P-Toluenesulfonamide SCHEMBL7370 | 0.64 | CA2 (1.00) | CA2CA9CA12CA1PTGS2 | |
| P-Toluenesulfonamide SCHEMBL1331323 | 0.64 | CA2 (1.00) | CA2CA9CA12CA1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |