SCHEMBL8633879

SCHEMBL8633879

CCCc1cc(Oc2cccc(OC)c2)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MTNR1B P49286 9/20 0.49
MTNR1A P48039 6/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HMGCR P04035 1/20 0.46
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5206395 0.89 HMGCR (0.50) MTNR1BMTNR1AHMGCRPOLBLMNA
SCHEMBL10366349 0.89 MTNR1A (0.56) MTNR1BMTNR1ASMN1; SMN2HMGCRKDM4E
SCHEMBL16648400 0.87 ALOX5 (0.49) MTNR1BMTNR1AHMGCR
SCHEMBL8634029 0.87 LTA4H (0.45) KDM4ELMNA
SCHEMBL2412893 0.86 LTA4H (0.47) HMGCR
SCHEMBL8635782 0.84 LTB4R (0.41) MTNR1BMTNR1ASMN1; SMN2KDM4E
SCHEMBL5204151 0.80 ALOX5 (0.43) MTNR1BMTNR1AHMGCRPOLB
SCHEMBL142945 0.79 MTNR1A (0.61) MTNR1BMTNR1ASMN1; SMN2HMGCRKDM4E
SCHEMBL5208689 0.79 ALOX5 (0.47)
SCHEMBL3550087 0.78 AKR1B1 (0.45) SMN1; SMN2HMGCRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed