Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701123 | 0.74 | ADRB2 (0.42) | HRH3ADRB2NCF1PLD1ITGB3 | |
| SCHEMBL8633904 | 0.73 | ADRB2 (0.36) | HRH3ADRB2NCF1PLD1ITGB3 | |
| SCHEMBL8636975 | 0.73 | ITGB3 (0.39) | ITGB3ITGA2BKDM4EALDH1A1CA12 | |
| SCHEMBL8838135 | 0.70 | ADRB2 (0.40) | HRH3ADRB2NCF1PLD1ITGB3 | |
| SCHEMBL8633897 | 0.69 | HRH3 (0.35) | HRH3ADRB2NCF1PLD1ITGB3 | |
| Hydrochloric Acid SCHEMBL8838142 | 0.69 | ADRB2 (0.41) | HRH3ADRB2NCF1PLD1ITGB3 | |
| SCHEMBL8636259 | 0.69 | NPY2R (0.35) | HRH3ITGB3ITGA2BALDH1A1CA12 | |
| SCHEMBL8634756 | 0.66 | ITGB3 (0.43) | HRH3ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL8633916 | 0.66 | ADRB2 (0.35) | ADRB2NCF1PLD1ITGB3ITGA2B | |
| SCHEMBL8776294 | 0.65 | ITGB3 (0.53) | ITGB3ITGA2BLMNACHRM1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |