Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636975 | 0.77 | ITGB3 (0.39) | ITGB3ITGA2BALDH1A1SMN1; SMN2AOC3 | |
| SCHEMBL8634756 | 0.69 | ITGB3 (0.43) | ITGB3ITGA2BHRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8633913 | 0.69 | HRH3 (0.35) | ITGB3ITGA2BHRH3ALDH1A1CA12 | |
| SCHEMBL8634084 | 0.67 | CA12 (0.40) | ITGB3ITGA2BHRH3SMN1; SMN2CA12 | |
| SCHEMBL8636258 | 0.66 | OPRM1 (0.36) | NPY2RITGB3ITGA2BHRH3ABCB1 | |
| SCHEMBL8702212 | 0.65 | CA12 (0.38) | ITGB3ITGA2BHRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8636260 | 0.65 | SPHK1 (0.35) | ITGB3ITGA2BHRH3CYP2C9TSHR | |
| SCHEMBL8635011 | 0.64 | ITGB3 (0.48) | ITGB3ITGA2BHRH3ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8837973 | 0.63 | ITGB3 (0.47) | ITGB3ITGA2BHRH3ALDH1A1AOC3 | |
| SCHEMBL8634711 | 0.62 | CA12 (0.44) | HRH3SMN1; SMN2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |