Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 5/20 | 0.33 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633897 | 0.76 | HRH3 (0.35) | ADRB2NCF1PLD1CHRM1ITGB3 | |
| SCHEMBL8636978 | 0.75 | ITGB3 (0.41) | CHRM1ITGB3ITGA2B | |
| SCHEMBL8636260 | 0.67 | SPHK1 (0.35) | CHRM1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8838066 | 0.67 | ITGB3 (0.43) | ADRB2NCF1PLD1ITGB3ITGA2B | |
| SCHEMBL8634088 | 0.67 | ITGB3 (0.36) | CHRM1ITGB3ITGA2B | |
| SCHEMBL8633913 | 0.66 | HRH3 (0.35) | ADRB2NCF1PLD1CHRM1ITGB3 | |
| SCHEMBL18788047 | 0.65 | RAMP1 (0.50) | ADRB2NCF1PLD1ITGB3ITGA2B | |
| SCHEMBL21197459 | 0.65 | RAMP1 (0.50) | ADRB2NCF1PLD1ITGB3ITGA2B | |
| SCHEMBL8634130 | 0.65 | ITGB3 (0.39) | ADRB2NCF1PLD1CHRM1ITGB3 | |
| SCHEMBL8701209 | 0.65 | L3MBTL1 (0.37) | ADRB2NCF1PLD1CHRM1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |