SCHEMBL8634083

SCHEMBL8634083

CC(OCCO)OC(C)OC(C)OCCO

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6700786 0.97 TSHR (0.35) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL17789995 0.86 ALDH1A1 (0.32) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL10964227 0.85
SCHEMBL10961944 0.85
SCHEMBL274489 0.85 LMNA (0.42) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL11790349 0.84 ALDH1A1 (0.31) ALDH1A1TSHRMAPK1
SCHEMBL11503836 0.84 ALDH1A1 (0.31) ALDH1A1TSHRMAPK1
SCHEMBL7279770 0.82
SCHEMBL28788474 0.82 MEN1 (0.52) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL8099939 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5853713-A Biologically compatible linear block copolymers of polyalkylene oxide and peptide units STERLING WINTHROP INC. (US) 1998-12-29 US disclosed
US-5618528-A Biologically compatible linear block copolymers of polyalkylene oxide and peptide units STERLING WINTHROP INC. (US) 1997-04-08 US disclosed
EP-0748226-A1 BLOCK COPOLYMERS NYCOMED IMAGING AS (NO) 1996-12-18 EP disclosed
WO-1995022991-A2 BLOCK COPOLYMERS NYCOMED IMAGING AS (NO) 1995-08-31 WO disclosed