Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768659 | 0.70 | KDM4E (0.35) | MAPTMEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL7991493 | 0.69 | ADORA2A (0.33) | MAPTMEN1KMT2ACYP1A2METAP2 | |
| SCHEMBL7545362 | 0.68 | CYP1A2 (0.30) | CYP1A2LMNA | |
| SCHEMBL8628040 | 0.67 | CYP2C9 (0.44) | MAPTNCOA1MEN1KMT2AKDM4E | |
| SCHEMBL8769280 | 0.66 | TDP1 (0.34) | CYP1A2LMNA | |
| SCHEMBL25271059 | 0.65 | ALDH1A1 (0.47) | MAPTMEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL3521491 | 0.63 | TDP1 (0.56) | DAOMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL30773497 | 0.62 | HTR1A (0.55) | MEN1KMT2ARHEBKDM4EALDH1A1 | |
| SCHEMBL2389927 | 0.62 | HTR1A (0.55) | MEN1KMT2ARHEBKDM4EALDH1A1 | |
| SCHEMBL22322658 | 0.62 | KMT2A (0.44) | MAPTMEN1KMT2ACYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824528-A1 | SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES WITH ARYLOXY OR ARYLTHIO SUBSTITUENTS | BAYER AG (DE) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035680-A1 | SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES WITH ARYLOXY OR ARYLTHIO SUBSTITUENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | disclosed |