Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634527 | 0.84 | — | — | |
| SCHEMBL5142630 | 0.72 | — | — | |
| SCHEMBL10938265 | 0.67 | CES2 (0.50) | SLC22A6ALDH1A1TP53ALOX15HSD17B10 | |
| SCHEMBL8637481 | 0.67 | LMNA (0.38) | LMNASLC22A6KDM4EUSP2ALDH1A1 | |
| SCHEMBL2335970 | 0.67 | LMNA (0.60) | LMNASLC22A6KDM4ECYP1A2BLM | |
| SCHEMBL8636296 | 0.65 | KDM4E (0.36) | LMNAKDM4EUSP2ALDH1A1CYP3A4 | |
| SCHEMBL2340198 | 0.65 | SLC22A6 (0.69) | LMNASLC22A6ALDH1A1CYP1A2BLM | |
| SCHEMBL15291832 | 0.65 | — | — | |
| SCHEMBL10598 | 0.65 | — | — | |
| SCHEMBL31384130 | 0.65 | ACE (0.36) | LMNAKDM4EGMNNUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770713-A | Phosphorothioate triester oligonucleotides and method of preparation | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-06-23 | — | — | US | disclosed |