Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636296 | 0.84 | KDM4E (0.36) | LMNAKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL10568538 | 0.67 | LMNA (0.43) | LMNAKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL3098037 | 0.67 | — | — | |
| SCHEMBL2335970 | 0.67 | LMNA (0.60) | LMNAKDM4EKMT2AHSD17B10TDP1 | |
| SCHEMBL10938265 | 0.67 | CES2 (0.50) | MEN1ALDH1A1KMT2AHSD17B10TDP1 | |
| SCHEMBL3218037 | 0.65 | — | — | |
| SCHEMBL2340198 | 0.65 | SLC22A6 (0.69) | LMNAALDH1A1KMT2ATSHRSLC22A6 | |
| SCHEMBL25423053 | 0.65 | ALDH1A1 (0.41) | LMNAKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL423978 | 0.65 | — | — | |
| SCHEMBL28472 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770713-A | Phosphorothioate triester oligonucleotides and method of preparation | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-06-23 | — | — | US | disclosed |
| US-3984404-A | Acylthiomethyl esters of cephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |