SCHEMBL8634701

SCHEMBL8634701

Cc1cc(OCC=C(Cl)Cl)ccc1Oc1ccc(OCC=C(Br)Br)c(C(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.35
RORC P51449 1/20 0.35
HTT P42858 1/20 0.34
THRA P10827 3/20 0.34
CASP1 P29466 1/20 0.32
PPARD Q03181 3/20 0.31
CARM1 Q86X55 2/20 0.31
KDM4E B2RXH2 2/20 0.31
PRMT6 Q96LA8 1/20 0.30
KMT2A Q03164 2/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
PPARG P37231 1/20 0.30
HTR2A P28223 1/20 0.30
SLC6A4 P31645 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8636900 0.94 THRB (0.39) THRBRORCHTTTHRACASP1
SCHEMBL8635872 0.80 THRB (0.41) THRBRORCTHRAKMT2AHTR2A
SCHEMBL8633877 0.79 THRB (0.39) THRBRORCHTTTHRAKMT2A
SCHEMBL8634914 0.79 THRB (0.42) THRBRORCHTTTHRAHTR2A
SCHEMBL8632642 0.78 LTA4H (0.42) THRBRORCHTTKMT2AL3MBTL1
SCHEMBL8632756 0.78 MAPT (0.39) THRBRORCKDM4EKMT2AL3MBTL1
SCHEMBL8635020 0.78 LTA4H (0.40) THRBRORCHTTKDM4EKMT2A
SCHEMBL8635018 0.78 THRB (0.40) THRBRORCHTTTHRAKMT2A
SCHEMBL8633770 0.78 PPARD (0.37) PPARDCARM1PRMT6
SCHEMBL8633931 0.78 HTT (0.39) HTTPPARDCARM1PRMT6PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed