Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026599 | 1.00 | TRPM8 (0.64) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL30903487 | 1.00 | TRPM8 (0.64) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL31591896 | 1.00 | TRPM8 (0.64) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL5026341 | 1.00 | TRPM8 (0.64) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL8631770 | 1.00 | TRPM8 (0.64) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL13619076 | 1.00 | TRPM8 (0.64) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL8632495 | 1.00 | TRPM8 (0.64) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL8630667 | 1.00 | TRPM8 (0.64) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL8630319 | 1.00 | TRPM8 (0.64) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL30903488 | 1.00 | TRPM8 (0.64) | TRPM8TRPA1EPHX1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010826-B | Stereoselective synthesis of perhydro-3, 6-dialkyl-2-benzo [ B ] furanones | 国际香料和香精公司 | 2024-08-13 | — | — | CN | claimed |
| US-10995080-B2 | Stereoselective synthesis of perhydro-3,6-dialkyl-2-benzo[b]furanones and analogs | INTERNATIONAL FLAVOR & FRAGRANCES INC. (US) | 2021-05-04 | — | — | US | claimed |
| US-20200377466-A1 | STEREOSELECTIVE SYNTHESIS OF PERHYDRO-3,6-DIALKYL-2-BENZO[B]FURANONES AND ANALOGS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-12-03 | — | — | US | claimed |
| EP-3744717-A1 | STEREOSELECTIVE PREPARATION OF PERHYDRO-3,6-DIMETHYL-2-BENZO[B]FURANONES | International Flavors & Fragrances Inc. (US) | 2020-12-02 | — | — | EP | claimed |
| CN-112010826-A | Stereoselective synthesis of perhydro-3, 6-dialkyl-2-benzo [ B ] furanones | 国际香料和香精公司 | 2020-12-01 | — | — | CN | claimed |
| CN-116675593-B | Method for selectively removing hydroxyl protecting group | 大连理工大学 | 2025-05-27 | — | — | CN | disclosed |
| CN-112010826-B | Stereoselective synthesis of perhydro-3, 6-dialkyl-2-benzo [ B ] furanones | 国际香料和香精公司 | 2024-08-13 | — | — | CN | disclosed |
| EP-4114815-B1 | HYDROBORATION-OXIDATION PROCESS | FIRMENICH & CIE (CH) | 2024-03-13 | — | — | EP | disclosed |
| CN-116675593-A | Method for selectively removing hydroxyl protecting group | 大连理工大学 | 2023-09-01 | — | — | CN | disclosed |
| EP-4114815-A1 | HYDROBORATION-OXIDATION PROCESS | Firmenich SA (CH) | 2023-01-11 | — | — | EP | disclosed |
| CN-115135629-A | Hydroboration-oxidation process | 弗门尼舍有限公司 | 2022-09-30 | — | — | CN | disclosed |
| US-10995080-B2 | Stereoselective synthesis of perhydro-3,6-dialkyl-2-benzo[b]furanones and analogs | INTERNATIONAL FLAVOR & FRAGRANCES INC. (US) | 2021-05-04 | — | — | US | disclosed |
| US-20200377466-A1 | STEREOSELECTIVE SYNTHESIS OF PERHYDRO-3,6-DIALKYL-2-BENZO[B]FURANONES AND ANALOGS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-12-03 | — | — | US | disclosed |
| EP-0621892-B1 | USE OF FURANONES AS SCENTING INGREDIENTS | FIRMENICH & CIE (CH) | 1998-07-08 | — | — | EP | disclosed |
| US-5464824-A | Odors and perfumed articles | FIRMENICH SA (CH) | 1995-11-07 | — | — | US | disclosed |
| WO-1994012143-A2 | USE OF FURANONES AS SCENTING INGREDIENTS | FIRMENICH SA (CH) | 1994-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10995080-B2 | Stereoselective synthesis of perhydro-3,6-dialkyl-2-benzo[b]furanones and analogs | DLD, DHCR7, DHPS | TRPM8 1179/4885TRPA1 1424/4885EPHX1 851/4885 |
| US-20200377466-A1 | STEREOSELECTIVE SYNTHESIS OF PERHYDRO-3,6-DIALKYL-2-BENZO[B]FURANONES AND ANALOGS | DLD, DHCR7, DHPS | TRPM8 1179/4885TRPA1 1424/4885EPHX1 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.