SCHEMBL13619076

SCHEMBL13619076

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nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 3/20 0.64
TRPA1 O75762 2/20 0.64
EPHX1 P07099 1/20 0.38
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.31
OPRM1 P35372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31026599 1.00 TRPM8 (0.64) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL30903487 1.00 TRPM8 (0.64) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL31591896 1.00 TRPM8 (0.64) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL5026341 1.00 TRPM8 (0.64) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL8631770 1.00 TRPM8 (0.64) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL8632495 1.00 TRPM8 (0.64) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL8630667 1.00 TRPM8 (0.64) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL8634813 1.00 TRPM8 (0.64) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL8630319 1.00 TRPM8 (0.64) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL30903488 1.00 TRPM8 (0.64) TRPM8TRPA1EPHX1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617763-B2 Hydroboration-oxidation process FIRMENICH SA (CH) 2026-05-05 US claimed
EP-4114815-B1 HYDROBORATION-OXIDATION PROCESS FIRMENICH & CIE (CH) 2024-03-13 EP claimed
US-20230120264-A1 HYDROBORATION-OXIDATION PROCESS FIRMENICH SA (CH) 2023-04-20 US claimed
CN-115135629-A Hydroboration-oxidation process 弗门尼舍有限公司 2022-09-30 CN claimed
US-12617763-B2 Hydroboration-oxidation process FIRMENICH SA (CH) 2026-05-05 US disclosed
EP-4114815-B1 HYDROBORATION-OXIDATION PROCESS FIRMENICH & CIE (CH) 2024-03-13 EP disclosed
US-20230202996-A1 SYNTHETIC METHODS FOR MAKING CARBOXYLIC ACIDS, ESTERS AND LACTONES P2 SCIENCE, INC. 2023-06-29 US disclosed
US-20230120264-A1 HYDROBORATION-OXIDATION PROCESS FIRMENICH SA (CH) 2023-04-20 US disclosed
EP-4114815-A1 HYDROBORATION-OXIDATION PROCESS Firmenich SA (CH) 2023-01-11 EP disclosed
CN-115135629-A Hydroboration-oxidation process 弗门尼舍有限公司 2022-09-30 CN disclosed
EP-1910261-B1 SUBSTITUTED CYCLOHEXANONES FIRMENICH & CIE (CH) 2009-11-11 EP disclosed
US-7470820-B2 Substituted cyclohexanones FIRMENICH SA (CH) 2008-12-30 US disclosed
US-7470820-B2 Substituted cyclohexanones FIRMENICH SA (CH) 2008-12-30 US disclosed
US-20080228008-A1 Substituted Cyclohexanones FIRMENICH SA (CH) 2008-09-18 US disclosed
US-20080228008-A1 Substituted Cyclohexanones FIRMENICH SA (CH) 2008-09-18 US disclosed
WO-2007010483-A1 SUBSTITUTED CYCLOHEXANONES FIRMENICH SA (CH) 2007-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230202996-A1 SYNTHETIC METHODS FOR MAKING CARBOXYLIC ACIDS, ESTERS AND LACTONES FDFT1, DLST, PCMT1 TRPM8 1032/4885TRPA1 677/4885EPHX1 1836/4885
US-20080228008-A1 Substituted Cyclohexanones NQO1, CYP2J2, CBR3 TRPM8 3536/4885TRPA1 983/4885EPHX1 742/4885
US-20230120264-A1 HYDROBORATION-OXIDATION PROCESS CYP11B2, HAO2, POR TRPM8 2573/4885TRPA1 1292/4885EPHX1 320/4885
US-12617763-B2 Hydroboration-oxidation process CFH, DOHH, AKR1B10 TRPM8 1508/4885TRPA1 1553/4885EPHX1 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.