SCHEMBL8634893

SCHEMBL8634893

CCON(C(=O)OC)c1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TP53 P04637 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP3A4 P08684 2/20 0.42
TRPM8 Q7Z2W7 1/20 0.42
TSHR P16473 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GAA P10253 2/20 0.39
DHODH Q02127 1/20 0.38
NOTUM Q6P988 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779792 0.85 TRPM8 (0.50) LMNAALDH1A1KDM4ETP53MEN1
SCHEMBL9175691 0.85 ALDH1A1 (0.44) LMNAALDH1A1KDM4ETP53MEN1
SCHEMBL8178829 0.84 KMT2A (0.42) LMNAALDH1A1KDM4ETP53MEN1
SCHEMBL8636800 0.81 ALDH1A1 (0.34) LMNAALDH1A1KDM4ETP53MEN1
SCHEMBL8173793 0.78 CYP3A4 (0.58) LMNAALDH1A1KDM4ETP53MEN1
SCHEMBL7601412 0.78 ALDH1A1 (0.44) LMNAALDH1A1KDM4ETP53MEN1
SCHEMBL11378935 0.77 KMT2A (0.44) LMNAALDH1A1KDM4ETP53MEN1
SCHEMBL9714447 0.76 ALDH1A1 (0.39) LMNAALDH1A1KDM4ETP53MEN1
SCHEMBL6130276 0.75 KMT2A (0.43) LMNAALDH1A1KDM4ETP53MEN1
SCHEMBL11493988 0.75 ALDH1A1 (0.40) LMNAALDH1A1KDM4ETP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704430-B1 N-substituted phenylcarbamic acid derivatives, a process for production thereof, agricultural and horticultural fungicides, intermediates of the derivatives and a process for production thereof NIHON NOHYAKU CO LTD (JP) 1998-07-29 EP disclosed
US-5712399-A N-substituted phenylcarbamic acid derivatives, a process for production thereof, agricultural and horticultural fungicides, intermediates of the derivatives and a process for production thereof NIHON NOHYAKU CO., LTD. (JP) 1998-01-27 US disclosed
US-5650434-A FUNGICIDES NIHON NOHYAKU CO., LTD. (JP) 1997-07-22 US disclosed
EP-0704430-A1 N-substituted phenylcarbamic acid derivatives, a process for production thereof, agricultural and horticultural fungicides, intermediates of the derivatives and a process for production thereof NIHON NOHYAKU CO., LTD. (JP) 1996-04-03 EP disclosed
EP-0619301-A2 N-Substituted phennylcarbamic acid derivates a process for production thereof, and agricultural and horticultural fungicides NIHON NOHYAKU CO., LTD. (JP) 1994-10-12 EP disclosed