Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175691 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TP53LMNAKDM4ECYP3A4 | |
| SCHEMBL8779792 | 0.77 | TRPM8 (0.50) | ALDH1A1TP53LMNAKDM4ECYP3A4 | |
| SCHEMBL10581172 | 0.77 | TP53 (0.35) | ALDH1A1TP53LMNAKDM4ECYP3A4 | |
| SCHEMBL8634893 | 0.76 | LMNA (0.47) | ALDH1A1TP53LMNAKDM4ECYP3A4 | |
| SCHEMBL9714755 | 0.74 | RIPK1 (0.37) | ALDH1A1TP53LMNAKMT2ARIPK1 | |
| SCHEMBL10700498 | 0.70 | MEN1 (0.35) | ALDH1A1TP53LMNAKDM4ECYP3A4 | |
| SCHEMBL7601412 | 0.68 | ALDH1A1 (0.44) | ALDH1A1TP53LMNAKDM4ECYP3A4 | |
| SCHEMBL9445898 | 0.68 | CYP3A4 (0.50) | ALDH1A1TP53LMNAKDM4ECYP3A4 | |
| SCHEMBL7194821 | 0.66 | ALDH1A1 (0.41) | ALDH1A1TP53LMNAKDM4ECYP3A4 | |
| SCHEMBL4769822 | 0.66 | KMT2A (0.44) | ALDH1A1TP53CYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116402-A | HERBICIDAL COMPOSITION CONTAINING DIOXOLANE, DIOXANE, OR DIOXEPANE DERIVATIVES AS ANTIDOTE | MAGYAR TUDOMANVOS AKADEMIA KOZPONTI KEMIAI KUTATO INTEZETE NITROKEMIA INARTELENEK FUZFOGYARTELEP (HU) | 1992-05-26 | — | — | US | claimed |
| US-5116402-A | HERBICIDAL COMPOSITION CONTAINING DIOXOLANE, DIOXANE, OR DIOXEPANE DERIVATIVES AS ANTIDOTE | MAGYAR TUDOMANVOS AKADEMIA KOZPONTI KEMIAI KUTATO INTEZETE NITROKEMIA INARTELENEK FUZFOGYARTELEP (HU) | 1992-05-26 | — | — | US | disclosed |