Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.43 |
| ▸ | CCR4 | P51679 | 5/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632809 | 0.91 | PI4KB (0.42) | PI4KBACLYSMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL8631448 | 0.91 | SMN1; SMN2 (0.40) | PI4KBACLYSMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL8630396 | 0.88 | PI4KB (0.44) | PI4KBCCR4PDE4APDE4BPDE4C | |
| SCHEMBL8630165 | 0.88 | ACLY (0.39) | PI4KBACLYPTGS1PTGS2ABCB11 | |
| SCHEMBL8627805 | 0.88 | PI4KB (0.38) | PI4KBACLYPTGS1PTGS2ABCB11 | |
| SCHEMBL8632910 | 0.86 | CCR4 (0.42) | PI4KBCCR4PDE4APDE4BPDE4C | |
| SCHEMBL8630562 | 0.86 | CCR4 (0.42) | PI4KBCCR4PDE4APDE4BPDE4C | |
| SCHEMBL8634518 | 0.85 | PI4KB (0.42) | PI4KBCCR4ACLYPDE4APDE4B | |
| SCHEMBL8632160 | 0.84 | CCR4 (0.41) | PI4KBCCR4ACLYPDE4APDE4B | |
| SCHEMBL8630479 | 0.84 | CCR4 (0.41) | PI4KBCCR4PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |