Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.43 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL8760874 | 0.85 | HCAR3 (0.39) | SMN1; SMN2MAPTHTTPOLBALDH1A1 | |
| SCHEMBL8639690 | 0.80 | SMN1; SMN2 (0.43) | GSTP1GSTM2SMN1; SMN2MAPTHTT | |
| SCHEMBL2977189 | 0.79 | ALDH1A1 (0.37) | MAPTPOLBALDH1A1NPSR1CYP1A2 | |
| SCHEMBL8635371 | 0.78 | HCAR3 (0.39) | SMN1; SMN2MAPTPOLBALDH1A1MAPK1 | |
| SCHEMBL2977058 | 0.77 | GSTP1 (0.39) | GSTP1GSTM2SMN1; SMN2MAPTHTT | |
| SCHEMBL3423746 | 0.76 | NSD2 (0.41) | GSTP1GSTM2SMN1; SMN2MAPTPOLB | |
| SCHEMBL7474447 | 0.76 | SMN1; SMN2 (0.44) | GSTP1GSTM2SMN1; SMN2MAPTHTT | |
| SCHEMBL7476700 | 0.76 | HTT (0.49) | SMN1; SMN2MAPTHTTPOLBALDH1A1 | |
| SCHEMBL3585555 | 0.76 | ALDH1A1 (0.36) | POLBALDH1A1NPSR1HPGDLMNA | |
| SCHEMBL2968993 | 0.76 | PRMT5 (0.39) | GSTP1GSTM2SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750782-A | ANTICARCINOGENIC AGENTS, ANTIHYPOXIC AGENTS, PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5739376-A | Fullerene derivatives, methods of preparing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| EP-0616609-B1 | NITROANILINE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | CANCER RES CAMPAIGN TECH (GB) | 1997-06-18 | — | — | EP | disclosed |
| US-5571845-A | Nitroaniline derivatives and their use as anti-tumour agents | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-11-05 | — | — | US | disclosed |
| EP-0616609-A1 | NITROANILINE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS. | CANCER RES CAMPAIGN TECH (GB) | 1994-09-28 | — | — | EP | disclosed |
| WO-1993011099-A1 | NITROANILINE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1993-06-10 | — | — | WO | disclosed |