Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633788 | 0.84 | — | — | |
| Bromide SCHEMBL8633449 | 0.73 | SNCA (0.33) | — | |
| SCHEMBL16043398 | 0.73 | HTR2C (0.33) | PDK2 | |
| SCHEMBL8633880 | 0.72 | AHR (0.44) | PDK2 | |
| SCHEMBL7651494 | 0.71 | PDK2 (0.37) | PDK2APOBEC3GPDCD1CD274 | |
| SCHEMBL8632446 | 0.70 | SLC6A4 (0.31) | — | |
| SCHEMBL7651499 | 0.69 | MPO (0.41) | PDK2APOBEC3G | |
| SCHEMBL8634750 | 0.69 | — | — | |
| SCHEMBL3545157 | 0.62 | AHR (0.31) | — | |
| SCHEMBL10558358 | 0.62 | ALOX5 (0.37) | PDK2APOBEC3GPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |