Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7632415 | 0.77 | — | — | |
| SCHEMBL848935 | 0.76 | ALOX5 (0.38) | AHRALOX5 | |
| SCHEMBL10687923 | 0.70 | MAPT (0.38) | — | |
| SCHEMBL8630321 | 0.70 | — | — | |
| SCHEMBL8636682 | 0.70 | — | — | |
| SCHEMBL25116194 | 0.70 | — | — | |
| SCHEMBL24275672 | 0.70 | AHR (0.40) | AHR | |
| SCHEMBL20714875 | 0.70 | MMP12 (0.36) | — | |
| SCHEMBL21399749 | 0.70 | MMP12 (0.33) | — | |
| SCHEMBL9875356 | 0.70 | AHR (0.40) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683070-B2 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | FMC CORPORATION (US) | 2010-03-23 | — | — | US | disclosed |
| US-20080090828-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | BAYER CROPSCIENCE AG (DE) | 2008-04-17 | — | — | US | disclosed |
| US-7300946-B2 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | BAYER CROPSCIENCE AG (DE) | 2007-11-27 | — | — | US | disclosed |
| EP-1572207-A4 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL) PIPERIDINES AND PYRIDINES | FMC CORP (US) | 2006-11-29 | — | — | EP | disclosed |
| US-20060135504-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | FMC CORPORATION | 2006-06-22 | — | — | US | disclosed |
| EP-1572207-A1 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL) PIPERIDINES AND PYRIDINES | FMC CORPORATION (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004060371-A1 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL) PIPERIDINES AND PYRIDINES | FMC CORPORATION (US) | 2004-07-22 | — | — | WO | disclosed |
| US-4772730-A | PYRAZOLINE INSECTICIDE INTERMEDIATES | FMC CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4772730-A | PYRAZOLINE INSECTICIDE INTERMEDIATES | FMC CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4730062-A | CYCLIZATION | FMC CORPORATION (US) | 1988-03-08 | — | — | US | disclosed |
| US-4730062-A | CYCLIZATION | FMC CORPORATION (US) | 1988-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135504-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | DDT, DRD4, QDPR | AHR 763/4885ALOX5 4032/4885 |
| US-20080090828-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | DDT, DRD4, QDPR | AHR 737/4885ALOX5 4032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.