SCHEMBL8635200

SCHEMBL8635200

CC(C)Oc1ccc(Oc2ccc(O)c(C(F)(F)F)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESRRA P11474 1/20 0.46
AR P10275 6/20 0.42
PNLIP P16233 1/20 0.42
ACACB O00763 4/20 0.40
ACACA Q13085 4/20 0.40
PTPN5 P54829 1/20 0.39
KMT2A Q03164 1/20 0.38
CYP3A4 P08684 1/20 0.37
CYP3A5 P20815 1/20 0.37
PDK2 Q15119 1/20 0.37
PARP10 Q53GL7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3719192 0.90 ALDH1A1 (0.43) ESRRAARPTPN5KMT2APDK2
SCHEMBL8637055 0.90 AR (0.43) ESRRAARPNLIPPTPN5KMT2A
SCHEMBL16648399 0.85 ESRRA (0.49) ESRRAAR
SCHEMBL8635438 0.82 LTA4H (0.50) ESRRAARKMT2A
SCHEMBL8633068 0.80 AR (0.49) ESRRAARPDK2
SCHEMBL8635974 0.80 ESRRA (0.46) ESRRAAR
SCHEMBL8633672 0.80 GAA (0.44) ESRRAARKMT2A
SCHEMBL8633319 0.79 ESRRA (0.54) ESRRAARKMT2A
SCHEMBL8636426 0.79 ESRRA (0.45) ESRRAARKMT2A
SCHEMBL8635710 0.78 LTA4H (0.54) ESRRAARKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP claimed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US claimed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP claimed
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed