SCHEMBL8635216

SCHEMBL8635216

COc1ccc(Oc2ccc(O)c(C(F)(F)F)c2)cc1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.50
TUBB P07437 1/20 0.50
TUBA3C P0DPH7 1/20 0.50
TUBA1B P68363 1/20 0.50
TUBA4A P68366 1/20 0.50
TUBB4B P68371 1/20 0.50
TUBB3 Q13509 1/20 0.50
TUBB2A Q13885 1/20 0.50
TUBB8 Q3ZCM7 1/20 0.50
TUBA3E Q6PEY2 1/20 0.50
TUBA1A Q71U36 1/20 0.50
TUBA1C Q9BQE3 1/20 0.50
TUBB6 Q9BUF5 1/20 0.50
TUBB2B Q9BVA1 1/20 0.50
TUBB1 Q9H4B7 1/20 0.50
AR P10275 10/20 0.48
ALDH1A1 P00352 1/20 0.48
GAA P10253 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632503 0.89 AR (0.48) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL8635438 0.85 LTA4H (0.50) ARALDH1A1GAAAPPESRRA
SCHEMBL16648399 0.85 ESRRA (0.49) ARALDH1A1ESRRA
SCHEMBL8632072 0.84 ESRRA (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL755578 0.81 ALDH1A1 (0.53) ARALDH1A1GAACA1CA2
SCHEMBL8633891 0.81 SMN1; SMN2 (0.50) ARALDH1A1GAAESRRA
SCHEMBL8636160 0.77 AR (0.42) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL126301 0.77 CA2 (0.76) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL8633068 0.77 AR (0.49) ARESRRA
SCHEMBL8635974 0.77 ESRRA (0.46) ARCA1CA2CA9ESRRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed