Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635447 | 0.91 | MTNR1B (0.67) | MTNR1BEPHX2HTR1ASLC6A4EED | |
| SCHEMBL8637780 | 0.88 | HTR1A (0.49) | MTNR1BEPHX2HTR1ASLC6A4POLB | |
| SCHEMBL8635640 | 0.85 | SLC6A4 (0.60) | MTNR1BHTR1ASLC6A4POLB | |
| SCHEMBL8638699 | 0.84 | HTR1A (0.56) | MTNR1BEPHX2HTR1ASLC6A4POLB | |
| SCHEMBL8633694 | 0.83 | SLC6A4 (0.55) | MTNR1BHTR1ASLC6A4EEDPOLB | |
| SCHEMBL8635354 | 0.83 | SLC6A4 (0.55) | MTNR1BEPHX2HTR1ASLC6A4POLB | |
| SCHEMBL8637331 | 0.82 | MTNR1B (0.71) | MTNR1BHTR1ASLC6A4LMNA | |
| SCHEMBL8633680 | 0.81 | HTR1A (0.56) | MTNR1BHTR1ASLC6A4SMN1; SMN2 | |
| SCHEMBL8636963 | 0.81 | HTR1A (0.61) | MTNR1BHTR1ASLC6A4POLBSMN1; SMN2 | |
| SCHEMBL8635044 | 0.80 | MTNR1B (0.65) | MTNR1BHTR1ASLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718286-B1 | 3-Alkoxybenzylpiperidine derivatives as melatonergic agents | BRISTOL MYERS SQUIBB CO (US) | 1998-07-29 | — | — | EP | claimed |
| EP-0718286-A1 | 3-Alkoxybenzylpiperidine derivatives as melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-26 | — | — | EP | claimed |