Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628489 | 0.85 | EGFR (0.44) | PDGFRBPDGFRAPOLBALDH1A1MAPK1 | |
| SCHEMBL8632136 | 0.80 | ALDH1A1 (0.49) | PDGFRBPDGFRAPOLBALDH1A1KDM4E | |
| SCHEMBL20871931 | 0.76 | TUBB4A (0.47) | ALDH1A1MAPK1ACHEKDM4ETSHR | |
| SCHEMBL8748534 | 0.73 | MAPK1 (0.51) | ALDH1A1MAPK1ACHEKDM4ETSHR | |
| SCHEMBL8659550 | 0.72 | POLB (0.50) | POLBALDH1A1PKMTSHRALOX5 | |
| SCHEMBL8748519 | 0.71 | CNR1 (0.49) | ALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL8748536 | 0.68 | ALDH1A1 (0.38) | POLBALDH1A1MAPK1ACHEKDM4E | |
| SCHEMBL9709038 | 0.65 | TSHR (0.59) | POLBALDH1A1MAPK1KDM4ETSHR | |
| SCHEMBL13453301 | 0.65 | POLB (0.59) | POLBALDH1A1ACHEPKMTSHR | |
| SCHEMBL82414 | 0.65 | POLB (0.59) | POLBACHEALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |