SCHEMBL674665

SCHEMBL674665

CCN(CC)CCCCN=Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.49
ALDH1A1 P00352 3/20 0.45
HPGD P15428 2/20 0.45
KCNH2 Q12809 4/20 0.43
CHRM2 P08172 1/20 0.43
HTR1A P08908 1/20 0.43
ADRA2A P08913 1/20 0.43
CHRM1 P11229 1/20 0.43
DRD1 P21728 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
ADRA1A P35348 1/20 0.43
OPRM1 P35372 1/20 0.43
DRD3 P35462 1/20 0.43
SLC6A3 Q01959 1/20 0.43
CA2 P00918 1/20 0.42
KDM4E B2RXH2 4/20 0.42
BCHE P06276 4/20 0.41
ACHE P22303 4/20 0.41
CACNA2D1 P54289 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673024 0.88 ALDH1A1 (0.47) SIGMAR1ALDH1A1HPGDKCNH2CHRM2
SCHEMBL22478597 0.83 KDM4E (0.45) SIGMAR1ALDH1A1HPGDKCNH2CHRM2
SCHEMBL8635393 0.83 SIGMAR1 (0.46) SIGMAR1CA2KDM4EBCHEACHE
SCHEMBL11477160 0.81 ALDH1A1 (0.41) ALDH1A1HPGDCA2KDM4EMEN1
SCHEMBL1120157 0.80 CA2 (0.49) ALDH1A1CA2KDM4EKMT2A
SCHEMBL1120158 0.80 CA2 (0.49) ALDH1A1CA2KDM4EKMT2A
SCHEMBL10899334 0.80 CA2 (0.55) ALDH1A1CA2KDM4EMEN1KMT2A
SCHEMBL11760622 0.80 CA2 (0.55) ALDH1A1CA2KDM4EMEN1KMT2A
SCHEMBL15172983 0.80 CA2 (0.55) ALDH1A1CA2KDM4EMEN1KMT2A
SCHEMBL12460453 0.80 CA2 (0.55) ALDH1A1CA2KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1873168-B1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORP (JP) 2012-12-12 EP claimed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US claimed
US-7671136-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-03-02 US claimed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US claimed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP claimed
US-20060025539-A1 Modified polymers prepared with lanthanide-based catalysts OZAWA YOICHI 2006-02-02 US claimed
US-6977281-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2005-12-20 US claimed
EP-1237935-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS Bridgestone Corporation (JP) 2002-09-11 EP claimed
WO-2001034659-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORPORATION (JP) 2001-05-17 WO claimed
CN-111051361-B Rubber composition 株式会社LG化学 2023-06-20 CN disclosed
EP-1873168-B1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORP (JP) 2012-12-12 EP disclosed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US disclosed
US-7671136-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-03-02 US disclosed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US disclosed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP disclosed
EP-1237935-B1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORP (JP) 2007-01-24 EP disclosed
US-20060025539-A1 Modified polymers prepared with lanthanide-based catalysts OZAWA YOICHI 2006-02-02 US disclosed
US-6977281-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2005-12-20 US disclosed
EP-1237935-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS Bridgestone Corporation (JP) 2002-09-11 EP disclosed
WO-2001034659-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORPORATION (JP) 2001-05-17 WO disclosed