Phencyclidine

Phencyclidine

SCHEMBL42022

c1ccc(C2(N3CCCCC3)CCCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 1.00
GRIN1 Q05586 5/20 1.00
GRIN2A Q12879 5/20 1.00
GRIN2B Q13224 5/20 1.00
PRCP P42785 3/20 1.00
GRIN2D O15399 1/20 1.00
GRIN3B O60391 1/20 1.00
CYP2B6 P20813 1/20 1.00
SLC6A2 P23975 1/20 1.00
SLC6A4 P31645 1/20 1.00
SLC6A3 Q01959 1/20 1.00
KCNH2 Q12809 1/20 1.00
GRIN2C Q14957 1/20 1.00
GRIN3A Q8TCU5 1/20 1.00
OPRM1 P35372 3/20 0.96
OPRD1 P41143 1/20 0.96
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
TP53 P04637 1/20 0.54
CYP1A2 P05177 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rolicyclidine SCHEMBL517928 1.00 SIGMAR1 (1.00) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL17008793 1.00 SIGMAR1 (1.00) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
SCHEMBL9153279 1.00 SIGMAR1 (1.00) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL5166553 0.98 SIGMAR1 (0.96) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL21777 0.98 OPRM1 (1.00) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL9431514 0.96 SIGMAR1 (0.92) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
SCHEMBL3407261 0.96 GRIN1 (0.92) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
SCHEMBL28282384 0.94 GRIN1 (0.88) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL28239746 0.93 GRIN1 (0.86) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL28294388 0.93 SIGMAR1 (0.86) SIGMAR1GRIN1GRIN2AGRIN2BPRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27262 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260141998-A1 METHOD FOR TRACKING, VERIFYING, AND AUTHENTICATING MULTI-STAGE CHAIN OF CUSTODY Courtfact, LLC (US) 2026-05-21 US claimed
EP-4121423-B1 TETRAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2026-04-29 EP claimed
US-12594388-B2 Device to deliver a predetermined amount of a substance to a natural orifice of the body APTARGROUP, INC. (US) 2026-04-07 US claimed
US-20260083361-A1 NON-INVASIVE DETERMINATION OF A PHYSIOLOGICAL STATE OF INTEREST IN A SUBJECT ISBRG CORP (CA) 2026-03-26 US claimed
US-20260085056-A1 OX1 RECEPTOR ANTAGONISTS NXERA PHARMA UK LIMITED (GB) 2026-03-26 US claimed
US-12582616-B2 Molecular targets for modulation of dissociative and associative states THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-03-24 US claimed
US-20260080800-A1 COMBINATION THERAPY WITH DIGITAL THERAPEUTICS FOR IMPROVED IMMUNE FUNCTION REMEPY HEALTH LTD (IL) 2026-03-19 US claimed
EP-4701593-A1 DIGITAL THERAPEUTICS Remepy Health Ltd (IL) 2026-03-04 EP claimed
US-12539337-B2 Nanostructure conjugates for modulation of location-specific subtypes of receptors and ion channels Molokanova, Elena (US) 2026-02-03 US claimed
US-20250332138-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDER VIVOZON, INC. (KR) 2025-10-30 US claimed
US-4459303-A ALLANTOIN-GLUTARALDEHYDE REACTION PRODUCT SUTTON LABORATORIES, INC. (US) 1984-07-10 US claimed
US-4446065-A CARBOXY OXIME OF 4-PHENYL-4-PIPERDINIOCYCLOHEXANONE SYVA COMPANY (US) 1984-05-01 US claimed
US-4399002-A Large organic cation-selective electrodes UNIVERSITY PATENTS, INC. (US) 1983-08-16 US claimed
US-4334526-A Method for administering a dissociative, unconscious type of anesthesia HAMACHER EDWARD N 1982-06-15 US claimed
EP-0046361-A1 New antimicrobial preservative compounds SUTTON LABORATORIES, INC. (US) 1982-02-24 EP claimed
US-4246894-A Method and system for administering a dissociative, unconscious type of anesthesia HAMACHER EDWARD N 1981-01-27 US claimed
US-4196185-A RADIOLABELED N-(4-HYDROXY-2-PHENYLETHYL)-4-(1-(PIPERIDINYL)CYCLOHEXYL)BENZAMIDE HOFFMANN-LA ROCHE INC. (US) 1980-04-01 US claimed
US-4110078-A CHLOROPLATINIC ACID, COBALTOUS THIOCYANATE, HYDROCARBON LIQUID ZELONIS PAUL THOMAS 1978-08-29 US claimed
US-4080693-A Embalming machine flow control apparatus PRUITT MIKE D 1978-03-28 US claimed
US-3940894-A Burial means and the like NUNES ABNER H 1976-03-02 US claimed